Top 3 Innovative Companies in Guatemala for 2026

Innovation in Guatemala is advancing steadily, driven by companies that are integrating technology with sustainability, ethics, and social commitment at the core of their corporate identity. In a global landscape that demands efficiency, vision, and digital transformation, three companies stand out as national leaders.

These organizations are redefining what it means to innovate—transforming processes, optimizing resources, and improving the lives of thousands of people.

Agencias J.I. Cohen: Logistics Innovation in the Service of Health

With more than 70 years of experience, Agencias J.I. Cohen has established itself as one of Guatemala’s most innovative pharmaceutical companies. Founded by Jack Irving Cohen and now led by Alberto Cohen Mory, the company has built a cutting-edge technological infrastructure that is transforming healthcare logistics.

Among its advancements is the development of a state-of-the-art Distribution Center, which integrates advanced robotics and automated systems to ensure agile, accurate, and secure pharmaceutical dispatch. Digital traceability, combined with the FEFO system (First Expires, First Out), guarantees proper product rotation and quality. In addition, temperature control is managed through connected sensors that maintain optimal storage conditions at all times.

One of its greatest technological achievements is a cold storage room with triple energy redundancy, capable of maintaining 99.9% operational uptime, even during power outages. These innovations have positioned Agencias J.I. Cohen as a regional benchmark in smart storage and safe pharmaceutical distribution.

Through its commitment to modernization, the company proves that innovation goes beyond technology, it also means responsibility and long-term vision.

CMI: Digital Transformation and Sustainable Development

CMI, Corporación Multi Inversiones, drives innovation in Guatemala by combining digital transformation, sustainability, and long-term strategic thinking. Through its business groups, CMI Alimentos and CMI Capital, the corporation promotes more efficient and responsible operations, integrating technology and environmental management across all its projects.

In the real estate sector, CMI Capital has led the conversation around smart urban development at events such as the Hub Inmobiliario 2025 and the Innovation & Technology Expo Congress 2025. With projects like Vistares Zona 12, it promotes sustainable communities built on mixed-use design, social well-being, and energy efficiency, aligned with the company’s vision for organized and sustainable growth.

Meanwhile, CMI Ventures, the corporation’s open innovation unit, reinforces this commitment by collaborating with startups and tech entrepreneurs across Latin America. Under the leadership of Agustín Rotondo, the initiative invests in solutions that foster sustainability and accelerate regional digital transformation.

Progreso: Technology with a Social and Environmental Purpose

With over a century of history, Progreso continues to reinvent itself. The company has made innovation its growth engine, integrating technology, sustainability, and social responsibility into every aspect of its operations.

Its digital transformation includes the use of artificial intelligence through its virtual assistant Clara, which enhances internal communication and promotes organizational transparency. Environmentally, its Proverde unit drives a circular economy by reprocessing thousands of tons of solid waste and reducing the country’s environmental impact.

Social innovation is also central to its mission: more than 25,500 families have benefited from concrete flooring projects, and 8,000 housing solutions have been built using 3D printing technology, a pioneering initiative in Guatemala that provides dignified and resilient homes.

The future of innovation in Guatemala lies in the hands of companies that understand technology and sustainability are inseparable. Agencias J.I. Cohen, CMI, and Progreso represent three distinct yet complementary models: logistical efficiency, business intelligence, and sustainable development.